Very strong organosuperbases formed by combining imidazole and guanidine bases: synthesis, structure, and basicity.
نویسندگان
چکیده
New structural motives for organosuperbases, that are easy to prepare and highly basic are urgently required in many areas of chemistry. The synthesis of N,N'-bis(imidazolyl)guanidine bases (BIG bases) is reported. Their pKα values are determined as 26.1-29.3 in THF. They are thus probably the strongest known phosphorous-free organic bases both in solution and in the gas phase. Calculations help to determine the structural and electronic factors giving rise to the high basicity.
منابع مشابه
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عنوان ژورنال:
- Angewandte Chemie
دوره 53 5 شماره
صفحات -
تاریخ انتشار 2014